Fertility Control by JoAnne S. Richards, Stephanie A. Pangas (auth.), Ursula-F.

By JoAnne S. Richards, Stephanie A. Pangas (auth.), Ursula-F. Habenicht, R. John Aitken (eds.)

The world’s inhabitants is becoming at an unsustainable price. From a baseline ?gure of 1 billion in 1800, international inhabitants is anticipated to exceed 9 billion by means of 2050 and 87. eight% of this progress might be localized in much less constructed nations. Such asymmetric inhabitants progress will yield a harvest of poverty, malnutrition, ailment and en- ronmental degradation that might impact us all. among the complicated mix of political, social, cultural and technological adjustments had to deal with this factor, the improvement of superior equipment of fertility law may be serious. The inadequacy of present contraceptive applied sciences is indicated by way of fresh facts s- gesting that the contraceptive wishes of over one hundred twenty million move unmet each year. As an instantaneous outcome of this de?cit 38% of pregnancies are unplanned and greater than 50% lead to an abortion, producing a complete of forty six million abortions every year rather between childrens. If secure, powerful contraceptives have been ava- in a position to each couple experiencing an unmet kin making plans want, 1. five million lives will be kept every year (UNFPA 2003). growth in contraceptive know-how aren't in basic terms generate better equipment of regulating fertility, yet must also offer quite a number easy methods to meet the altering wishes of the world’s inhabitants. Contraceptive perform used to be revo- tionized in 1960 within the US and 1961 in Europe via the advent of the oral contraceptive capsule by means of Gregory Pincus, MC Chang and co-workers, in accordance with enjoyable- psychological hormone learn performed in Germany.

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34 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Abstract Estrogens influence fertility and infertility in animals. This chapter reviews the use of estrogen as a contraceptive through the regulation of its production and action. It is concluded that the use of specific agonists and antagonists of estrogen action that avoid the global and unwanted side effects of estrogen offers new potential methods of contraception.

1 Regulation of Estrogen Production . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Regulation of Estrogen Action . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 5 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 References . . . . . . . . . . . . . . . . . . . . . . . . .

30 Cellular Mechanisms of Action . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Estrogens and Contraception . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Regulation of Estrogen Production . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Regulation of Estrogen Action . . . . . . . . . . . . . . . . . . . . . . . . . .

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